Volume 27, Issue 3 (In Press 2026)
Arch Rehabil 2026, 27(3): 422-445 |
Back to browse issues page
Ethics code: IR.MUI.REC.1395.2.260
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Jafarian F S, Sadeghi Demneh E. Effect of Orthotic Interventions on Pain Intensity and Hand Function in People With De Quervain’s Tenosynovitis: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Arch Rehabil 2026; 27 (3) :422-445
URL: http://rehabilitationj.uswr.ac.ir/article-1-3735-en.html
URL: http://rehabilitationj.uswr.ac.ir/article-1-3735-en.html
1- Musculoskeletal Research Center, School of Rehabilitation Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
2- Musculoskeletal Research Center, School of Rehabilitation Sciences, Isfahan University of Medical Sciences, Isfahan, Iran. ,sadeghi@rehab.mui.ac.ir
2- Musculoskeletal Research Center, School of Rehabilitation Sciences, Isfahan University of Medical Sciences, Isfahan, Iran. ,
Abstract: (1713 Views)
Objective De Quervain’s tenosynovitis (DQT) is a common hand tendinopathy associated with pain and functional impairments. Orthotic interventions are commonly prescribed as a conservative approach; however, clinical evidence regarding their effectiveness remains limited. This study aimed to investigate the efficacy of orthotic interventions on pain and hand function in people with DQT through a systematic review and meta-analysis of randomized clinical trials (RCTs).
Materials & Methods This is systematic review and meta-analysis. A comprehensive search was carried out in the PubMed, Web of Science, and Scopus databases for relevant RCTs published from 2000 to 2025. Methodological quality was assessed using the Cochrane risk of bias tool (RoB 2). Meta-analysis was carried out in Review Manager software. For each outcome measure, standardized mean differences (SMDs) and 95% confidence intervals (CIs) were reported.
Results Among 125 RCTs initially found, 13 were included in the review. Overall, 662 participants were enrolled across the included studies, representing a wide range of ages and clinical characteristics of DQT patients. Meta-analysis of four studies demonstrated that thump splints combined with corticosteroid injection (CSI) or neurotherapy resulted in a significant reduction in pain in the short-Term (Mean difference=-2.75, 95% CI, -3.21%, -2.29%, P<0.001). However, there was no significant difference in long-term (mean difference=-0.34, 95% CI, -1.4%, 0.73%, P=0.54).
Conclusion Thump splint use combined with CSI or neurotherapy has a short-term (one-month) effect on pain reduction and hand function improvement in patients with DQT. However, further well-designed RCTs are required to clarify the long-term efficacy of orthotic interventions.
Materials & Methods This is systematic review and meta-analysis. A comprehensive search was carried out in the PubMed, Web of Science, and Scopus databases for relevant RCTs published from 2000 to 2025. Methodological quality was assessed using the Cochrane risk of bias tool (RoB 2). Meta-analysis was carried out in Review Manager software. For each outcome measure, standardized mean differences (SMDs) and 95% confidence intervals (CIs) were reported.
Results Among 125 RCTs initially found, 13 were included in the review. Overall, 662 participants were enrolled across the included studies, representing a wide range of ages and clinical characteristics of DQT patients. Meta-analysis of four studies demonstrated that thump splints combined with corticosteroid injection (CSI) or neurotherapy resulted in a significant reduction in pain in the short-Term (Mean difference=-2.75, 95% CI, -3.21%, -2.29%, P<0.001). However, there was no significant difference in long-term (mean difference=-0.34, 95% CI, -1.4%, 0.73%, P=0.54).
Conclusion Thump splint use combined with CSI or neurotherapy has a short-term (one-month) effect on pain reduction and hand function improvement in patients with DQT. However, further well-designed RCTs are required to clarify the long-term efficacy of orthotic interventions.
Type of Study: Systematic Review |
Subject:
Orthotics & Prosthetics
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
Copyright © The Author(s);
This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 (CC-By-NC 4.0), which permits use, distribution, and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
Contact Information
This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 (CC-By-NC 4.0), which permits use, distribution, and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
Contact Information
