Mental disorders are present in a large percentage of the older adults and psychotherapeutic medications are most commonly used to manage behavioral problems. Elderly leads to multiple chronic diseases, disability, declining function and frailty that affecting it. Chronologic age is only one determinant of the changes pertinent to drug therapy that occur in older people. Drug usage patterns also change as a result of the increasing incidence of disease with age and tendency to prescribe heavily for patients in hospitals and old folks’ homes. General changes in the lives of older people have significant effect on the way of the medications is used too. This article discusses about drug metabolism (with specific consideration on the psychotropic drugs), psychotropic drugs consumption and prescription in elderly with psychiatric disorders wl.ich use to various articles.