Objective: The aim of this study is to review the previous implemented research on drug abuse and dependency in Iran.

Materials & Methods: In this study all available information has been used instructions, official says, rules, etc.

Results: Addiction is a major problem in our country in a severe and urgent intervention requires. Due to the difficulty of longer research and prevention of addiction, Preventive and social studies are small. A significant number of researches in the field of addiction treatment, the country have been done. Due to the nature of disaster-pron country as earthquakes, floods, and the drug, most efforts are focused on drug control .That the poor predictions of future changes in material consumption and future ongoing monitoring is necessary. The prevalence of injection use has increased compared to non-injecting drug users in Iran and 15 to 23 percent are infected with HIV. In most studies, the cost of addiction treatment and direct costs of addiction treatment is considered and costs such as fighting, prevention, and drug trafficking is not considered.

Conclusion: Due to the favorable attitude in our society, rules, and guidelines related, it is necessary the proper planning and comprehensive research on prevention and treatment in addition to the executive must be done.